{"id":620,"date":"2025-05-08T11:43:01","date_gmt":"2025-05-08T09:43:01","guid":{"rendered":"https:\/\/irem.uma.es\/?page_id=620"},"modified":"2026-02-23T09:45:57","modified_gmt":"2026-02-23T08:45:57","slug":"research-2","status":"publish","type":"page","link":"https:\/\/irem.uma.es\/?page_id=620","title":{"rendered":"Investigaci\u00f3n"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"620\" class=\"elementor elementor-620\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bbd4290 e-flex e-con-boxed e-con e-parent\" data-id=\"bbd4290\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4a3cc9a e-con-full e-flex e-con e-child\" data-id=\"4a3cc9a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-161e11b e-con-full e-flex e-con e-child\" data-id=\"161e11b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-983ffce e-con-full animated-fast e-transform e-flex elementor-invisible e-con e-parent\" data-id=\"983ffce\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeIn&quot;,&quot;_transform_scale_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.01,&quot;sizes&quot;:[]},&quot;animation_delay&quot;:0,&quot;_transform_scale_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\">\n\t\t<div class=\"elementor-element elementor-element-cf8f280 e-con-full e-flex e-con e-child\" data-id=\"cf8f280\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-442457c e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"442457c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-7bac14a e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"7bac14a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3dc9971 elementor-widget elementor-widget-heading\" data-id=\"3dc9971\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Mecanismos cerebrales en la adicci\u00f3n a opi\u00e1ceos<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a74c16 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"6a74c16\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Por el consumo de sustancias opi\u00e1ceas se producen cambios en distintas regiones cerebrales, siendo algunos irreversibles. Nuestro grupo de investigaci\u00f3n est\u00e1 interesado en saber c\u00f3mo interaccionan diferentes sistemas de neurotransmisi\u00f3n (dopamin\u00e9rgico y opioide) para tratar de prevenir las alteraciones conductuales y f\u00edsicas asociadas al uso de estas sustancias.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-379ba5a e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"379ba5a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInLeft&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e93954f elementor-widget elementor-widget-image\" data-id=\"e93954f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"900\" src=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon.jpg\" class=\"attachment-full size-full wp-image-921\" alt=\"\" srcset=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon.jpg 1200w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-300x225.jpg 300w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-1024x768.jpg 1024w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-768x576.jpg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1da62fd e-flex e-con-boxed e-con e-parent\" data-id=\"1da62fd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-67359a3 e-con-full e-flex e-con e-child\" data-id=\"67359a3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-35b7ec4 e-con-full e-flex e-con e-child\" data-id=\"35b7ec4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2e185d9 e-con-full animated-slow e-transform e-flex elementor-invisible e-con e-parent\" data-id=\"2e185d9\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeIn&quot;,&quot;_transform_scale_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.01,&quot;sizes&quot;:[]},&quot;animation_delay&quot;:0,&quot;_transform_scale_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27db5e1 elementor-widget elementor-widget-image\" data-id=\"27db5e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"313\" src=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-1024x400.jpg\" class=\"attachment-large size-large wp-image-946\" alt=\"\" srcset=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-1024x400.jpg 1024w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-300x117.jpg 300w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-768x300.jpg 768w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-1536x600.jpg 1536w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/36752-2048x800.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc3a1b6 e-flex e-con-boxed e-con e-child\" data-id=\"cc3a1b6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9173c07 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"9173c07\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-0a0cc03 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"0a0cc03\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ef31c6e elementor-widget elementor-widget-heading\" data-id=\"ef31c6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Regulaci\u00f3n de la nocicepci\u00f3n y la analgesia<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d1e31f elementor-widget elementor-widget-text-editor\" data-id=\"1d1e31f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>La nocicepci\u00f3n es la capacidad de nuestro cuerpo de percibir est\u00edmulos potencialmente da\u00f1inos, como es el dolor, y poder responder ante ellos. Y la analgesia es la inhibici\u00f3n o eliminaci\u00f3n de esa percepci\u00f3n, ya sea fisiol\u00f3gicamente o mediante el uso de medicamentos. Estamos investigando c\u00f3mo las fibras del dolor (nociceptores) y las neuronas en la m\u00e9dula espinal comunican y transmiten esa se\u00f1al dolorosa, y as\u00ed buscar dianas para desarrollar nuevas terapias farmacol\u00f3gicas.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-48e6c47 e-con-full e-flex e-con e-child\" data-id=\"48e6c47\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d2e435c e-flex e-con-boxed e-con e-parent\" data-id=\"d2e435c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4bf6651 e-con-full e-flex e-con e-child\" data-id=\"4bf6651\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3f34546 e-con-full e-flex e-con e-child\" data-id=\"3f34546\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-46e4409 e-con-full animated-fast e-transform e-flex elementor-invisible e-con e-parent\" data-id=\"46e4409\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeIn&quot;,&quot;_transform_scale_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.01,&quot;sizes&quot;:[]},&quot;animation_delay&quot;:0,&quot;_transform_scale_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\">\n\t\t<div class=\"elementor-element elementor-element-5f801b0 e-con-full e-flex e-con e-child\" data-id=\"5f801b0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-3325404 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"3325404\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-e041cc1 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"e041cc1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2814b10 elementor-widget elementor-widget-heading\" data-id=\"2814b10\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Modulaci\u00f3n dopamin\u00e9rgica del estre\u00f1imiento inducido por opioides<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ac491b1 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"ac491b1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Esta l\u00ednea de investigaci\u00f3n se centra en el estudio del estre\u00f1imiento inducido por opioides (EIO) y en la identificaci\u00f3n del receptor dopamin\u00e9rgico D<sub>4<\/sub> (D<sub>4<\/sub>R) como posible diana terap\u00e9utica adyuvante durante el tratamiento con morfina. Se analizan las alteraciones funcionales, neuronales y estructurales del colon en modelos animales, con el objetivo de desarrollar estrategias que reduzcan los efectos secundarios intestinales sin comprometer la analgesia de los tratamientos.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dd16f08 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"dd16f08\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInLeft&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1562dca elementor-widget elementor-widget-image\" data-id=\"1562dca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"900\" src=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon.jpg\" class=\"attachment-full size-full wp-image-921\" alt=\"\" srcset=\"https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon.jpg 1200w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-300x225.jpg 300w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-1024x768.jpg 1024w, https:\/\/irem.uma.es\/wp-content\/uploads\/2025\/06\/2210.i203.008.F.m004.c9.addictions-bad-habits-cartoon-768x576.jpg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Mecanismos cerebrales en la adicci\u00f3n a opi\u00e1ceos Por el consumo de sustancias opi\u00e1ceas se producen cambios en distintas regiones cerebrales, siendo algunos irreversibles. Nuestro grupo de investigaci\u00f3n est\u00e1 interesado en saber c\u00f3mo interaccionan diferentes sistemas de neurotransmisi\u00f3n (dopamin\u00e9rgico y opioide) para tratar de prevenir las alteraciones conductuales y f\u00edsicas asociadas al uso de estas sustancias. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-620","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/pages\/620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/irem.uma.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=620"}],"version-history":[{"count":138,"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/pages\/620\/revisions"}],"predecessor-version":[{"id":1684,"href":"https:\/\/irem.uma.es\/index.php?rest_route=\/wp\/v2\/pages\/620\/revisions\/1684"}],"wp:attachment":[{"href":"https:\/\/irem.uma.es\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}